EndoCleave, rec., GMP Grade, AOF

from Serratia marcescens, recombinant, expressed in E.coli, solution

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Unlock excellence in viral vector production with EndoCleave

EndoCleave is a recombinant endonuclease, expressed in E. coli, that digests DNA and RNA. EndoCleave is primarily designed for use in the digestion of nucleic acids (from host cells and plasmids) during viral vector production and purification for gene therapy.

EndoCleave is developed in a fit-for-purpose format and provides the performance, quality, and scale you need for your viral vector production and any other biopharma applications where nucleic acid digestion is needed.

Produced using validated manufacturing and cleaning processes up to the final filling step and released under stringent final QC checks. Know that you are getting consistent quality every time.

From the generation of the master cell bank to the final filling, noanimal-derived materials are used in the process. This greatly simplifies your risk analysis.

During fermentation, no antibiotics are used. Therefore, allergic reactions to antibiotics is not a factor in your overall risk analysis.

Tested during final QC-release for the absence of impurities such as RNases, proteases, host cell protein, bioburden, heavy metals, or endotoxins. Work with an enzyme at peak performance that poses no risk to downstream processing.

We work with you to provide the necessary technical documents for your regulatory submissions.

Changing reagent quality between pre-clinical development and commercialization poses a risk. Secure your processes by using the best available quality from the start.

Ordering Information

Technical documents

for certificates, method sheets (instructions for use), safety data sheets and software downloads
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