For further processing only. Others RNase Inhibitor rec GMP Grade AOF RNase Inhibitor, rec., GMP Grade, AOF PID00000124 from rat lung, expressed in E. coli, solution 09537589103 RNase Inhibitor rec. GMP Grade AOF, 2 MU RNase Inhibitor rec. GMP Grade AOF Reagents, kits 2 MU (50 mL) Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "RNase Inhibitor, rec., GMP Grade, AOF, 2 MU". Unit of measure is "piece". 09537643103 RNase Inhibitor rec. GMP Grade AOF,100kU RNase Inhibitor rec. GMP Grade AOF Reagents, kits 100 kU (2.5 mL) Not Available CustomBiotech product. Please contact your local representative. Will be supplied as "RNase Inhibitor, rec., GMP Grade, AOF, 100 kU". Unit of measure is "piece". 142298-75-7 en RNase Inhibitor protects RNA from RNases, be it in molecular diagnostics assays or during in vitro mRNA synthesis for therapeutics and vaccines. en RNase Inhibitor boosts the performance of RNA-based applications. The protein effectively blocks ubiquitious RNases, thereby enhancing the sensitivity of RNA-based molecular diagnostic assays or protecting mRNA synthesized by in vitro transcription.RNase Inhibitor is part of every preparative mRNA synthesis from lab-scale to industrial scale, for example in the synthesis of COVID-19 vaccines. en Use the enzyme in the synthesis of mRNA for therapeutics or vaccines. It is designed to meet specific needs of the pharmaceutical industry (fit-for-purpose):animal-origin-free (AOF)free of antibioticsextended testing for impuritiesmanufactured under GMPsupplied with supplementary documents for regulatory submissions. en Appearance: Clear, colorless solutionVolume activity (according to Blackburn by inhibition of the hydrolysis of cCMP by RNAse A): > 40 kU/mLUnit definition: One unit of RNase Inhibitor activity is defined as the amount which inhibits 50% of the activity of 5 ng RNase A.Specific activity: > 80 kU/mg proteinPurity (SDS PAGE): > 95%Unspecific nucleases (up to 400 U using MWM III-DNA/1 h/37°C): Not detectable.Nicking activity (up to 400 U using pBR 322-DNA/1 h/37°C): Not detectable.RNase activity (up to 400 U using MS 2-RNA/1 h/37°C): Not detectableRNase activity after thermal inactivation (10 min/65°C): Not detectable up to 400 U using MS 2-RNA/1 h/37°CPerformance test on LightCycler® (PBGD system): Corresponds to specificationEndotoxins: ≤ 10 EU/mLBioburden: ≤ 10 CFU/mLE.coli HC DNA: ≤ 100 pg/mg proteinE.coli HC protein: ≤ 50 ppmHeavy metals (Ni, Co, V): ≤ 10 ppmProteases (50 μg/15 min/37°C): Not detectableStability: At -15 to -25°C within specification range for 18 months from date of manufacture. en